COA literature and instrument review
Literature and critical instrument reviews are both central components to the development and selection of COAs for inclusion in studies. The Adelphi Values Patient-Centered Outcomes team have vast experience performing all types of COA literature and instrument reviews to meet a range of purposes, including:
- Reviews of qualitative evidence to support disease/conceptual model development and initial selection of instruments
- Instrument reviews in which relevant instruments are identified and critically evaluated
- Gap analysis involving mapping existing instruments against a conceptual model or target product profile
- Systematic reviews of COA data – for example, to understand the evidence regarding ability to detect change over time for a given COA.
In the past 5 years we have conducted over 80 COA literature reviews, of which over 50 were instrument reviews specifically focused on identification and review of COA instruments.
We possess the flexibility of thinking to ensure any review is ‘fit for purpose’, and tailored to fit the client’s goals while meeting budget and timeline requirements. Scope can vary from being ‘targeted’ through to comprehensive, ‘systematic’ reviews.
Bennett B M, Wells J R, Panter C, Yuan Y, Penrod J R. The Humanistic Burden of Small Cell Lung Cancer (SCLC): A Systematic Review of Health-Related Quality of Life (HRQoL) Literature. Front Pharmacol (2017) 8; 339
Eek D, Krohe M, Mazar I, Horsfield A, Pompilus F, Friebe R, Shields AL. Patient-reported preferences for oral versus IV administration for the treatment of cancer: a review of the literature. Patient Preference and Adherence (2016) 10; 1609-1621
Taylor F, Reasner DS, Carson RT, Deal LS, Foley C, Iovin R, Lundy JJ, Pompilus F, Shields AL, Silberg D, on behalf of the Patient-Reported Outcome Consortium’s Functional Dyspepsia Working Group. Development of a symptom-based patient-reported outcome instrument for functional dyspepsia: A preliminary conceptual model and an evaluation of the adequacy of existing instruments. The Patient (2016) 5; 409-418
Arbuckle R, Carson R, Abetz-Webb L, Hyams J, Di Lorenzo C, Lewis B, Gargon E et al. Measuring the symptoms of pediatric constipation and irritable bowel syndrome with constipation: expert commentary and literature review. The Patient (2014) 7; 343-364