Development of a value slide set in restless leg syndrome (RLS) Global value dossier and e-v@luate platform development in RLS PRO and Health Economics (HE) consulting on global health outcomes in RLS Development of a sleep measure for a labelling claim in RLS Linguistic validation management of the Restless Leg… Read More
Our Expertise
Development of a payer value proposition and materials in psoriasis NICE submissions for a new biologic for the treatment of moderate to severe psoriasis in the UK Systematic literature review of quality of life in psoriasis Manuscript on a literature review of quality of life in psoriasis Literature review and… Read More
Global value dossier update in multiple sclerosis (MS) Multiple technology appraisal in MS for NICE Research into UK data sources for MS Delphi study (with KOL and payer interviews) to inform market access strategy in MS Utility elicitation study on patients with MS Validation of three cost-effectiveness and budget impact… Read More
Manuscript on the understanding of payers and pricing in lupus nephritis PRO consulting in lupus for labelling claims Assessing utility for flares in systemic lupus erythematosus in the UK, France, Spain, Australia and Canada, including training and managing local interviewing agencies and providing support to local teams Key opinion leader… Read More
Pre-budget impact analysis in personalised medicine (biomarkers) for inflammatory bowel diseases… Read More
Core value dossier to support new treatment in hidradenitis suppurativa Update to a value proposition deck with adolescent data in hidradentis suppurativa Core value dossier, payer value proposition and objection handler update in hidradenitis suppurativa Structured literature review and value dossier updates in a biosimilar for hidradenitis suppurativa Payer value… Read More
Development of an FDA dossier in X-Linked Hypophosphatemia (XLH) Validation activities of an FDA dossier in XLH Psychometric validation of the Brief Pain Inventory (BPI) and Western Ontario and McMaster osteoarthritis index (WOMAC) in XLH using online survey data Exploration of content validity of PROMIS items for use in children… Read More
Review and input into a statistical analysis plan and two clinical study reports in relation to PRO analyses for a trial of an adjunctive therapy in patients with tuberous sclerosis complex who have refracory partial-onset seizures Post hoc analyses for a trial of an adjunctive therapy in patients with tuberous… Read More
Understanding the experience of the mucopolysaccharidosis I (MPS I) patient to improve outcome assessments: evidence from the literature and treatment experts Cognitive debriefing interviews on the Mucopolysaccharidosis Health Assessment Questionnaire (MPS-HAQ) Evaluating the MPS-HAQ for use in patient registries to support EMA regulatory commitments… Read More
Understanding and documenting the disease burden of metachromatic leukodystrophy Support of patient survey study development among patients with metachromatic leukodystrophy Web-based survey implementation and analytic consulting support in metachromatic leukodystrophy Clinical outcome assessment strategy development and validation in metachromatic leukodystrophy… Read More
Exploration of IQ as a relevant endpoint in Hunter’s syndrome Endpoint review in Hunter’s syndrome PRO dossier on the Disease Activity Score (DAS), Scales of Independent Behaviour-Revised (SIB-R), Behaviour Rating Inventory of Executive Function (BRIEF) and Vineland Adaptive Behaviour Scales (VABS) for Hunter’s syndrome Strategic PRO and ObsRO analysis of… Read More
Real-world evidence toolkit in Transthyretin Familial Amyloid Polyneuropathy (TTR-FAP)… Read More
Health economic analysis for SMC resubmission in homocystinuria… Read More
Payer value proposition, payer value dossier and cost effectiveness model in acromegaly Landscape analysis of acromegaly patient registries Adequacy of the Acromegaly Quality of Life Questionnaire (AcroQoL) as an endpoint in acromegaly: endpoint review & strategic recommendations Analysis of PRO data to support clinical trial dissemination activities in acromegaly Consultancy… Read More
Payer research into a new treatment for mucopolysaccharidosis III (San Filippo syndrome) Preliminary consulting on endpoints in San Filippo syndrome Endpoint review and caregiver interviews in San Filippo syndrome Participation in a meeting to provide consultation on a paediatric PRO in San Filippo syndrome Strategic PRO and ObsRO analysis of… Read More
Value dossier update for a treatment in phenylketonuria (PKU) Updating of a cost manuscript for PKU Value strategy, landscape analysis, health economic model and value dossier development for PKU Development of a poster on a Delphi Panel in PKU Payer research, payer/KOL interviews and rapid assessment of an opportunity in… Read More
Pricing and reimbursement dossier for a treatment for Niemann-Pick disease type-C… Read More
Development of the evidence base regarding treatment patterns, cost and burden of disease for patients with hereditary angioedema to support the use of a new treatment Communications package in hereditary angioedema Clinical endpoint review, recommendations and update of an FDA submission package in hereditary angioedema Hereditary angioedema clinical trial endpoint… Read More
Payer research to understand evidence requirements for reimbursement in Gaucher’s disease HTA recommendations analysis in Gaucher’s disease Development and validation of a questionnaire in Gaucher’s disease… Read More
Global value dossier in the treatment of Fabry’s disease Strategic literature review in Fabry’s disease Development of a PRO questionnaire to assess gastrointestinal symptoms of Fabry’s disease Survey administration in an observational study to evaluate gastrointestinal symptoms of Fabry’s disease Strategic consultancy on a protocol for Fabry’s disease Consulting agreement… Read More