Central nervous system and neurology

Evaluation of patients with insufficient efficacy and/or tolerability to triptans for the acute treatment of migraine: A systematic literature review.
Leroux E, Buchanan A, Lombard L, Loo LS, Bridge D, Rousseau B, Hopwood N, Matthews B, Reuter U.
Advances in Therapy, October 2020

Treatment Options for Dementia with Lewy bodies: A Network Meta-Analysis of Randomised Control Trials.
Tahami Monfared A, Desai M, Hughes R, Lucherini S, Yi Y, Perry R.
Neurol Ther (2020).

The use of healthcare resource utilization costs for treatment-resistant depression as evidence for decision-making in the Canadian healthcare system.
Zhang Q, O’Hara M, Zante D, Pone E, Fadeyi I, Hopwood N, Perry R.
Poster presented at the virtual 2020 CADTH Symposium

Burden of Disease and Current Management of Dementia with Lewy Bodies: A Literature Review
Tahami Monfared AA, Meier G, Perry R, Joe D
Neurol Ther 8, 289–305 (2019)

Use of antipsychotic blood levels in clinician decision making: A cross-over study using clinical vignettes of patients with schizophrenia
Savitz A, Melkote R, Riley R, Pobre MA, McQuarrie K, Williamson D, Banderas B
Psychiatry Res. 2018; 267:25-29

Novel integrative approach combining patient, physician and empirical assessments for diagnosing secondary progressive multiple sclerosis
Meier DP, Bennett B, Tolley C, Kilgariff S, Tomic D, Ziemssen T
Poster presented at the 7th Joint Congress of the European Committee for Treatment and Research in Multiple Sclerosis–Americas Committee for Treatment and Research in Multiple Sclerosis, Paris, France, 25–28 October, 2017.

Cultural relevance of the global impact of Dravet syndrome in Australia, Italy, the US and UK
Nabbout R, Auvin S, Cross JH, Guerrini R, Scheffer I, Thiele E, Chiron C, Irwin J, Mistry A, Williamson N, Grimes R, Bennett B
European Paediatric Neurology Society (EPNS) conference

Development and content validation of a  preliminary core set of patient- and caregiver-relevant outcomes for inclusion in a potential composite endpoint for Dravet syndrome
Nabbout R, Auvin S, Chiron C, Irwin J, Mistry A, Williamson N
Epilepsy & Behavior. 2017; 78: 232-242

A qualitative assessment of key symptoms associated with the progression from RRMS to SPMS by physicians and patients
Ziemssen T, Bennett B, Tolley C, Kilgariff S, Simsek D, Lahoz R, Verdun Di Cantogno E
Poster presented at the American Academy of Neurology, Vancouver, Canada, 15-21 April 2016

Challenges in the health economics of acute pain: A rapid review of the literature
Braileanu G, Johnson BC, Ashraf S, Borrill J, Hirst M
Poster presented at International Society for Pharmacoeconomics and Outcomes Research (ISPOR), Vienna, Austria, 29th Oct-2nd Nov 2016

Development of the multiple sclerosis (MS) Early Mobility Impairment Questionnaire (EMIQ)
Ziemssen T, Phillips G, Shah R, Mathias A, Foley C, Coon C, Sen R, Lee A, Agarwal S
J Neurol (2016) 263: 1969. doi:10.1007/s00415-016-8210-4

Responder analyses of droxidopa in patients with symptomatic neurogenic orthostatic hypotension
Rowse GJ, Hewitt A, Shields AL, Freeman R, Kaufmann H
Poster presented at the 68th annual meeting of The American Academy of Neurology Annual Meeting in Vancouver, Canada

Towards a composite clinical endpoint: Identifying a core set of patient and caregiver relevant outcome measures through qualitative research on the global impact of Dravet syndrome
Nabbout R, Auvin S, Chiron C, Irwin J, Mistry A, Williamson N
Poster presented at: European Congress on Epileptology, Prague 2016

Responder analyses of droxidopa in patients with symptomatic neurogenic orthostatic hypotension
Rowse GJ, Hewitt A, Shields AL, Freeman R, Kaufmann H
Movement Disorders. 30(10):e7, SEP 2015

Assessing the impact of caring for a person with schizophrenia: Development of the Schizophrenia Caregiver Questionnaire
Gater A, Rofail D, Marshall C, Tolley C, Abetz-Webb L, Zarit SH, Berardo CG
Patient. 2015 Feb 14.

The feasibility of using electronic clinical outcome assessments in people with schizophrenia and their informal caregivers
Tolley C, Rofail D, Gater A, Lalonde JK
Patient Related Outcome Measures 2015, 6:91—101

Development and validation of the fatigue symptoms and impacts questionnaire – relapsing multiple sclerosis (FSIQ-RMS™)
Stokes J, Schuler R, Yaworsky A, Hunsche E
Poster session presented at: International Society for Pharmacoeconomics and Outcomes Research (ISPOR), 19th Annual International Congress, Montréal, Canada, 1-3 June 2014

Psychometric analyses to inform item reduction and evaluate sensitivity of the Early Mobility Impairment Questionnaire for multiple sclerosis
Phillips G, Mathias A, Coon C, Agarwal S, Sen R, Shah R, Ziemssen T
Poster session presented at: International Society for Pharmacoeconomics and Outcomes Research (ISPOR), 17th Annual European Congress, Amsterdam, Netherlands, 8-12 November 2014

Psychometric testing of the Early Mobility Impairment Questionnaire for multiple sclerosis
Ziemssen T, Mathias A, Coon C, Agarwal S, Shah R, Phillips G
Poster presented at the 6th Triennial Joint Meeting of ACTRIMS and ECTRIMS, Boston, USA, 10-13 September 2014

Sometimes it’s difficult to have a normal life: Results from a qualitative study exploring caregiver burden in schizophrenia
Gater A, Rofail D, Tolley C, Marshall C, Abetz-Webb L, Zarit SH, Berardo CG
Schizophr Res Treatment. 2014;2014:368215. Epub 2014 Apr 3

The effect of vortioxetine on health-related quality of life (HRQoL) in patients with major depressive disorder (MDD)
Florea I, Danchenko N, Loft H, Rive B, Pendlebury S, Abetz L
Poster session presented at: International Society for Pharmacoeconomics and Outcomes Research (ISPOR), 18th International Meeting, New Orleans, USA, 20 -22 May 2013

A decision aid to assist decisions on disclosure of mental health status to an employer: protocol for the CORAL exploratory randomised controlled trial
Henderson C, Brohan E, Clement S, Williams P, Lassman F, Schauman O, Murray J, Murphy C, Slade M, Thornicroft G
BMC Psychiatry 2012;12:133

Anticipated discrimination among people with schizophrenia
Uçok A, Brohan E, Rose D, Sartorius N, Leese M, Yoon CK, Plooy A, Ertekin BA, Milev R, Thornicroft G; INDIGO Study Group
Acta Psychiatr Scand 2012;125:77

Assessing health-related quality of life (HRQoL) in major depressive disorder (MDD): Do commonly used instruments meet EMA requirements for psychometric properties and content relevance
Danchenko N, Rive B, Pendlebury S, Abetz L
Poster session presented at: International Society for Pharmacoeconomics and Outcomes Research (ISPOR), 17th Annual International Meeting, Washington, USA, 2-6 June 2012

Association between public views and reactions to mental illness and self-stigma among individuals in 14 European countries
Evans-Lacko S, Brohan E, Mojtabai R, Thornicroft G
Psychol Med 2012;42:1741

Development and psychometric properties the Barriers to Access to Care Evaluation scale (BACE) related to people with mental ill health
Clement S, Brohan E, Jeffery D, Henderson C, Hatch S L, Thornicroft G
BMC Psychiatry 2012;12:36

Reliability and validity of the Japanese version of the Children’s Depression Rating Scale-Revised (CDRS-R)
Denda K, Fujii Y, Nakato Y, Kako Y, Tanaka T, Crawford B
Saishin Seishin Igaku (Newest Psychiatric Medicine) 2012; 17 (1): 51-58

Stigma and discrimination: Critical human rights issues for mental health
Randall J, Thornicroft G, Brohan E, Kassam A, Lewis-Holmes E
In M. Dudley, D. Silove & Gale F (Eds.) Mental Health and Human Rights. Oxford University Press, Oxford 2012

Systematic review of beliefs, behaviours and influencing factors associated with disclosure of a mental health problem in the workplace
Brohan, E, Wheat K, Henderson C, Malcolm E, Barley E, Clement, S, Slade M, Thornicroft G
BMC Psychiatry 2012;12:11

Systematic review of pain measurement strategies to support product labeling in US regulated clinical trials
Shields AL, Stokes J, Caron M, Emery M
Poster session presented at: 31st Annual Conference of the American Pain Society, Honolulu, USA, 16-19 May 2012

The effect of vortioxetine (LU AA21004) on health-related quality of life (HRQoL) in patients with major depressive disorder (MDD)
Florea I, Danchenko N, Loft H, Rive B, Pendlebury S, Abetz L
Poster session presented at: International Society for Pharmacoeconomics and Outcomes Research (ISPOR), 17th Annual International Meeting, Washington, USA, 2-6 June 2012

The impact of spina bifida on caregivers
Rofail D, Maguire L, Heelis R, Colligs A, Lindemann M, Abetz L
Neurol Ther 2012;1:4

Disability hate crime and targeted violence and hostility: a mental health and discrimination perspective
Clement S, Brohan E, Sayce L, Pool J, Thornicroft G
J Ment Health 2011;20:219

Employers’ attitudes to people with mental health problems in the workplace in Britain: Changes between 2006 and 2009
Little K, Henderson C, Brohan E, Thornicroft G
Epidemiol Psychiatr Sci 2011;20:73

Pediatric restless legs syndrome: Analysis of symptom descriptions and drawings
Picchietti D L, Arbuckle RA, Abetz L, Durmer J S, Ivanenko A, Owens J A, Croenlein J, Allen R P, Walters AS
J Child Neurol 2011;26:1365-76

Reported stigma and discrimination by people with a diagnosis of schizophrenia
Rose D, Willis R, Brohan E, Sartorius N, Villares C, Wahlbeck K, Thornicroft G; INDIGO Study Group
Epidemiol Psychiatr Sci 2011;20:193

Self-stigma, empowerment and perceived discrimination among people with bipolar disorder or depression in 13 European countries: the GAMIAN-Europe study
Brohan E, Gauci D, Sartorius N, Thornicroft G; GAMIAN-Europe Study Group
J Affect Disord 2011;129:56

Use of pain instruments as endpoints in regulatory submissions: implications of the US FDA’s new patient reported outcomes (PRO) Guidance
Black PM, Shields, AL, Halling K
Poster presented at the 30th Annual Scientific Meeting of the American Pain Society. Austin, TX, USA, May 19 – 21, 2011

Translatability assessment of the post-migraine questionnaire
Lambe J, Acquadro C, Conway K, Ng-Mak D, Healy C, Norquist J, Fitzgerald K, Banderas B, Evans C, Kornstein A
Value Health 2011;14:A214

An interpretative phenomenological analysis of the psychological ramifications of hand-arm vibration syndrome
Ayers B, Forshaw M
J Health Psychol 2010;15:533

Caregiver burden in Alzheimer’s disease
Ito D, Stokes J, Piault-Louis E, Bonnet P
Poster session presented at: Alzheimer’s Association International Conference on Alzheimer’s Disease , Honolulu, USA, 10-15 July 2010

Cognitive impairment associated with schizophrenia: The humanistic and economic burden
Rofail D, Kitchen H, Heyes A, Heron L, Sacco P
Poster session presented at: American Neurological Association 135th  Annual Meeting, San Francisco, USA, 12-15 September 2010

Cost-utility analysis of refinamide versus topiramate and lamotrine for the treatment of children with Lennox-Gastaut syndrome in the United Kingdom
Verdian L, Yi Y
Seizure 2010; 19(1):1-11

Development of a caregiver burden assessment in Alzheimer’s disease
Ito D, Stokes J, Piault E
Poster session presented at: 62nd Annual Meeting of the American Academy of Neurology, 10–17 April 2010

Development of the Pediatric Restless Legs Syndrome Severity Scale (P-RLS-SS): A patient-reported outcome measure of pediatric RLS symptoms and impact
Arbuckle R, Abetz L, Durmer J, Ivaneko A, Owens J, Croenlein J, Bolton K, Moore A, Allen RP, Walters A, Picchietti D
Sleep Medicine 2010;11:897-906

Development of the Pediatric Restless Legs Syndrome Severity Scale (P-RLS-SS): A patient-reported outcome measure of pediatric RLS symptoms and impact
Arbuckle R, Abetz LA, Picchietti DL, Durmer JS, Ivanenko A, Owens JA, Croenlein J, Bolton K, Moore A, Allen RP, Walters AS
Oral presentation at: 33rd  Sleep Conference, San Antonio, USA, June, 2010: A314

Employees with mental health problems: Survey of U.K. employers’ knowledge, attitudes and workplace practices
Brohan E, Henderson C, Little K, Thornicroft G
Epidemiol Psichiatr Soc 2010;19:326

Experiences of mental illness stigma, prejudice and discrimination: A review of measures
Brohan E, Slade M, Clement S, Thornicroft G
BMC Health Serv Res 2010;10:80

Measuring mental illness stigma
Brohan E, Slade M, Clement S, Thornicroft G
In G. Thornicroft & M Tansella (Eds.) Mental Health Outcome Measures (3rd edition), Royal College of Psychiatry, Oxford 2010

Mental illness and the workplace: Conceal or reveal?
Wheat K, Brohan E, Henderson C, Thornicroft G
J R Soc Med 2010;103:83

Pediatric restless legs syndrome: Qualitative analysis of symptom descriptions and drawings
Picchietti DL, Arbuckle R, Abetz LA, Durmer JS, Ivanenko A, Owens JA, Croenlein J, Allen RP, Walters AS
Poster  session presented at: 33rd Sleep Conference, San Antonio, USA, June, 2010: A341

Self-stigma, empowerment and perceived discrimination among people with schizophrenia in 14 European countries: the GAMIAN-Europe study
Brohan E, Elgie R, Sartorius N, Thornicroft G, GAMIAN-Europe Study Group
Schizophr Res 2010;122:232

Stigma and discrimination
Thornicroft, G, Metha, N, Brohan, E, Kassam A
In Bhugra D & Morgan C (Eds.) Principles of Social Psychiatry (2nd edition) Wiley-Blackwell 2010;331

Stigma and discrimination of mental health problems: Workplace implications
Brohan E, Thornicroft G
Occup Med (Lond) 2010;60:414

Alzheimer’s disease treatment: Assessing caregiver preferences for mode of treatment delivery
Abetz L, Rofail D, Mertzanis P, Heelis R, Rosa K, Tellefsen C, Roborel de Climens A, McBurney C, Thomas S
Adv Ther 2009;26:627

Global pattern of experienced and anticipated discrimination against people with schizophrenia: A cross-sectional survey
Thornicroft G, Brohan E, Rose D, Sartorius N, Leese M; INDIGO Study Group
Lancet 2009;31;373:408

Helpseeking and stigma – A broader view
Clement S, Brohan E, Thornicroft G
The Psychologist 2009;22:192

Public attitudes and the problem of stigma
Thornicroft G, Brohan E, Kassam A
In M.G. Gelder,  Lopez-Ibor JJ, Andreasen NC and Geddes J, (Eds.) New Oxford Textbook of Psychiatry (2nd edition), Oxford University Press, Oxford 2009

Stigma and schizophrenia – Authors’ reply
Thornicroft G, Brohan E, Rose D, Sartorius N, Leese M
Lancet 2009;373:1336

The psychometric validation of the Sheehan Disability Scale (SDS) in patients with bipolar disorder
Arbuckle R, Frye MA, Brecher M, Paulsson B, Rajagopalan K, Palmer S, Degl’ Innocenti A
Psychiatry Res 2009;165:163

Validation of the sleep impact scale in patients with major depressive disorder and insomnia
Lasch K, Joish VN, Zhu Y, Rosa K, Qiu C, Crawford B
Curr Med Res Opin 2009;25:1699

Eliciting utility scores for health states associated with Lennox-Gastaut syndrome
Yi Y, Verdian L, Oyee J, Tolley K, Heyes A
Value in Health 2008; 11 (6): A606

Rufinamide in the adjunctive treatment of Lennox-Gastaut syndrome (LGS): A cost effectiveness analysis
Yi Y, Verdian L, Jansen JP
Value in Health 2008; 11 (6): A605